New MCCS Clinical Publication: Standardised Dosing Guidance for Medical Cannabis Oils
November 24, 2025 | IN NEWS | BY Kate Thorpe
The Medical Cannabis Clinicians Society has released an important new clinical reference text for prescribers: Medical Cannabis Oils: Dosing and Guidance for Safe and Effective Treatment in Adults and Children.
This comprehensive handbook brings together clear, evidence-based protocols for dosing, titrating, and monitoring medical cannabis promoting safe practice in real-world settings. It is now available as a PDF and Kindle eBook, with a print edition to follow.
Why this handbook matters
Prescribers working with medical cannabis oils have not had a single, structured, practical resource to guide dosing and titration. This publication fills that gap with detailed dosing tables for twelve commonly treated conditions, including chronic pain, epilepsy, autism, anxiety, headache, and sleep disorders.
It also sets out step-by-step recommendations for safe initiation, titration, monitoring, managing adverse effects, recognising drug interactions, and applying harm-reduction principles.
The handbook is edited by Dr Evan Cole Lewis, paediatric and adult neurologist and Assistant Professor at the Hospital for Sick Children and the University of Toronto, and Dr Rowan Thompson, Resident Doctor. Both are members of the Society’s Executive Committee and bring extensive experience in cannabinoid medicine. Other members of the Committee contributed clinical insights, case experience and technical input throughout the development of the handbook.
The text marries up-to-date evidence in condition-specific medical cannabis dosing with the collective expertise of key prescribers who have treated thousands of patients. Together this knowledge has helped shape this practical, evidence-informed resource that reflects real-world UK and North American prescribing practices. The guide provides clear, structured protocols that support safe prescribing in everyday clinical environments, with safety and clarity at the centre of its approach.
For many clinicians, formal teaching on the endocannabinoid system and cannabis-based medicines was absent from undergraduate and postgraduate training. This handbook closes that knowledge gap, giving prescribers a solid foundation for dosing cannabis oils, titrating confidently, and adjusting treatment to optimise patient outcomes.
A milestone for clinical practice
This publication represents a significant step forward for clinicians working with cannabis-based medicines in the UK and North America. It sets out standardised guidance shaped by the experience of prescribers who have been practising safely and effectively for many years.
The handbook aligns with the Society’s CPD-accredited medical cannabis training programme and supports clinicians to deliver consistent, evidence-based care across a wide range of conditions.
Clinicians are encouraged to use the handbook alongside two key MCCS resources:
- The Good Practice Guide for Prescribers of CBPMs
- The MCCS in-person CPD-accredited training programme, presented monthly by Professor Barnes
Together, these resources provide a unified framework for safe, consistent prescribing across the UK.
Part of a growing series
A second publication in this series is already being developed: Medical Cannabis Flower (Flos), minor cannabinoids and terpenes: Dosing and Guidance for Safe and Effective Treatment. This follow-on text will provide detailed protocols for prescribing inhaled cannabis products and is expected in the coming months.
Buy Medical Cannabis Oils: Dosing and Guidance for Safe and Effective Treatment in Adults and Children.
This key resource for all prescribers of medical cannabis in the UK is available to buy now:
- PDF: via the MCCS Shopify site
- Kindle eBook: via Amazon
- Print edition: coming soon
MCCS members can access an exclusive discount code for the PDF edition via the Members’ Hub. Please note, this is a professional clinical reference and not a patient-facing guide.
Hear from the editors in our upcoming webinar
A free webinar, hosted by the handbook’s editors Dr Evan Cole Lewis and Dr Rowan Thompson, is taking place on 15 January, 2026 at 7pm. The session will walk through how to use the new dosing guide in practice, covering titration strategies, start-low-go-slow principles, when to introduce THC, and how to apply the handbook’s clinical frameworks safely.